Platelet rich plasma therapy for hair loss

Platelet-rich plasma (abbreviation: PRP) is blood plasma that has been enriched with platelets. As a concentrated source of autologous platelets, PRP contains several different growth factors and other cytokinesthat can stimulate healing of bone and soft tissue. As of 2016, no large-scale randomised controlled trials have confirmed the promise of PRP in basic science and preclinical trials to treat musculoskeletal injuries (including tendinitis, nerve injuries), help in bone grafting or androgenic hair loss.

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Platelet-rich plasma therapy is an old therapy and used extensively in specialities of dermatology, orthopedics and dentistry. Platelet rich plasma therapy utilizes growth factors present in alpha granules of platelets in an autologous manner. Main indications in dermatology for PRP are androgenetic alopecia, wound healing, face rejuvenation etc. For preparation of PRP, various protocols are used and no standard protocol exists but main principles essentially involve concentrating platlets in a concentration of 3–5 times the physiological value and then injecting this concentrated plasma in the tissue where healing or effect is desired